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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease multiple endocrine neoplasia type 1
Comorbidity C0242363|pancreatic endocrine tumor
Sentences 5
PubMedID- 20566584 men1 in pancreatic endocrine tumors: analysis of gene and protein status in 169 sporadic neoplasms reveals alterations in the vast majority of cases.
PubMedID- 23645327 An understanding of the current causes of death is important to tailor treatment for these patients and to help identify prognostic factors; however, it is generally lacking.to add to our understanding, we conducted a detailed analysis of the causes of death and prognostic factors from a prospective long-term national institutes of health (nih) study of 106 men1 patients with pancreatic endocrine tumors with zollinger-ellison syndrome (men1/zes patients) and compared our results to those from the pooled literature data of 227 patients with men1 with pancreatic endocrine tumors (men1/pet patients) reported in case reports or small series, and to 1386 patients reported in large men1 literature series.
PubMedID- 22584720 Surgical approaches to pancreatic endocrine tumors associated with multiple endocrine neoplasia type 1 may differ greatly from those applied to sporadic pancreatic endocrine tumors.
PubMedID- 22797396 Context: the surgical management of pancreatic endocrine tumors in patients with multiple endocrine neoplasia type 1 (men-1) is controversial and complicated by the fact that these tumors are frequently multifocal.
PubMedID- 22563225 Recently reported that meningiomas developed in 6 of 74 (8%) men1 patients with pancreatic endocrine tumors (pets) prospectively.

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